Argireline Amplified Peptide Serum Booster

Argireline Amplified is Acetyl Hexapeptide-8 in a liposomal delivery system. You blend it into your own base at 2 to 5% to soften the look of expression lines — forehead, crow's feet, and the creases between the brows.

This is a formulation ingredient, not a finished serum. Do not apply it undiluted.

What is in the bottle

INCI: Water (Aqua), Acetyl Hexapeptide-8, Sodium Benzoate

Three ingredients. Sodium benzoate is the preservative.

Clear, thin liquid. Water-soluble. Paraben-free. Made in Spain. 0.5 oz blue glass dropper bottle.

The science: Acetyl Hexapeptide-8 and the SNARE complex

The published research on Acetyl Hexapeptide-8 centres on the SNARE complex — the protein assembly that mediates signalling at the neuromuscular junction. Acetyl Hexapeptide-8 has been studied for its interaction with SNARE complex formation, and that is the mechanism the supplier's research programme is built around.

We publish this because our customers are formulators and informed buyers who want to know what the ingredient actually is, not just what a label says about it.

What the supplier's research reports

Lipotec's efficacy work on Argireline Amplified Peptide Solution includes a study using a 3D bio-printed muscle model, led by Dr. Samuel Sánchez at the Institute of Bioengineering of Catalonia. In that model the amplified formulation showed measurable relaxation activity and reduced post-expression time compared with the original.

The supplier's studies also report up to a 20% reduction in wrinkle depth over 28 days with amplified formulations.

These findings are the manufacturer's, from their efficacy dossier, and are reproduced here under our licence agreement with them. They describe testing of the raw material, not of any finished product you blend at home — your result depends on the concentration you use, your base, and how consistently you apply it.

How much to add

Recommended usage rate is 2 to 5%. Using our house rate of 9 drops per 1% per fluid ounce:

Full conversions on the serum booster chart.

Where it works

• Anti-aging moisturisers
• Multifunctional serums
• Eye creams and gels
• Body lotion
• Facial masks

Amplified or original — which one

Both are Acetyl Hexapeptide-8. The difference is how it is delivered and how much you use.

Pick the original if you are new to peptides, your skin is on the sensitive side, or you want the most formula for the money.

Pick Amplified if you want the liposomal delivery and would rather use less product per batch.

Neither is wasted money. They are the same active.

Blending with other peptides

Argireline Amplified layers with Snap-8, Syn-Ake and Inyline — all four work on the look of expression lines through different routes, so stacking them is not doubling up. Keep the combined total sensible.

Storage

Refrigerate on arrival. The blue glass keeps light out.

For external use only. Cosmetic grade. Do not apply undiluted to skin. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Argireline is a registered trademark of Lipotec S.A.U., used under licence.